Brands Names: Levitra, Staxyn
Levitra is the new generation drug for the treatment of erectile dysfunction which belongs to the group of phosphodiesterase type 5 inhibitors (PDE5 inhibitor). The drug is appointed to men who experience erection problems during sexual contact, which caused by either psychological reasons or due to persistent stress and fatigue.
Composition and form of release
The active ingredient of this drug is vardenafil. It was developed for the treatment of erectile dysfunction by Bayer Pharmaceuticals. The drug was marketed under the brand name Levitra and became one of the main opponents of the famous Viagra. The drug is available in tablet form with dosages of 5 mg, 10 mg, and 20 mg.
The mechanism of action of Levitra is to block the production of cGMP-specific phosphodiesterase type 5 enzyme and allow blood to flow to the penis. However, the effect occurs only in the presence of sexual stimulation. The maximum concentration of vardenafil in the blood is reached 30–90 minutes after taking the medicine. Alcohol and food intake does not significantly affect the pharmacokinetics of vardenafil.
Levitra intended for use in men over 18 years. The recommended daily dose of the drug is 10 mg or half a tablet. The maximum dose is 20 mg. The drug should be taken 20-30 minutes before sexual intercourse and washed down with water. The effect of the drug lasts about 5 hours, regardless of the use of alcoholic drinks and food. Doctors recommend men over 65 years of age to start taking Levitra with ¼ tablets and adjust the dosage according to the individual tolerance of the drug.
Levitra is contraindicated for men with diseases of the cardiovascular system or anatomical anomalies of the structure of the penis. The drug should not be taken by people with high sensitivity to the individual components of the drug, and in the case of severe forms of liver or kidney disease.
Interaction with other drugs
Drugs containing vardenafil in minimal doses (up to 5 mg) can be used only 6 hours after taking erythromycin, ketoconazole or itraconazole alpha blockers. It is strictly forbidden to take Levitra together with nitric oxide donors and nitrate-containing agents as well as indinavir and ritonavir.
Levitra is usually well-tolerated by patients. The side effects of this drug are minimal, and they gradually pass with regular use. Approximately 1–10% of patients experienced headaches, dizziness, and hyperemia. Less common side effects are nasal congestion, dyspepsia, and nausea caused by indigestion.