Levitra box

Levitra Pills

Generic Name: Vardenafil
Brands Names: Levitra, Staxyn

What is Levitra?

Levitra is indicated as a treatment of erectile dysfunction and belongs to the group of phosphodiesterase type 5 inhibitors (PDE5 inhibitor). The drug is appointed to men who experience erection problems during sexual contact, and could be caused by either psychological reasons or due to persistent stress and fatigue.

Erection occurs due to the relaxation of smooth muscles and the filling of the penis with the maximum amount of blood. Unlike other similar drugs, Levitra is highly compatible with fatty foods and alcohol, and the effect occurs within a 20-30 minutes frame after its admission. As such, Levitra is ideal for the most demanding users.

Composition and form of release

The active substance of the drug is vardenafil hydrochloride trihydrate. The drug is available in the form of coated tablets, and comes in dosages of 5 mg, 10 mg, and 20 mg.

Pharmacological effect

The active substance of the drug selectively inhibits type 5 phosphodiesterase, which causes a cleavage of the cyclic guanosine monophosphate. This indirectly facilitates the relaxation of the smooth muscles of the cavernous bodies, and allows an influx of blood into the penis during sexual stimulation.

Clinical data

The drug was showed to have high effectiveness among its pharmacological group. Efficacy of the drug was up to 92% among patients with erectile dysfunction of varying degrees, depending on the dosage. High therapeutic results were also obtained in patients with diabetes mellitus (72%), in patients with prostatectomy (71%), in patients with severe impotence (72%), and in patients with resistance to Viagra (62%).


Levitra is used in the treatment of violations pertaining to the sexual function in men (impotence or erectile dysfunction, lack of ability to achieve and retain an erection).


The drug should not be used in cases of hypersensitivity to the components in the drug, or when there are medical contraindications to sexual intercourse.

Use Levitra with caution in cases of:

  • Diseases of the cardiovascular system, heart rhythm disturbances, congestive heart failure, a case of a recent heart attack, apoplexy, in the presence of a QT prolonged interval syndrome, with increased or decreased arterial pressure;
  • Liver disease;
  • Kidney disease, in case of being on dialysis;
  • Diseases of blood cells, such as sickle cell anemia, multiple myeloma or leukemia, blood clotting disorders (hemophilia);
  • Chronic diseases of the gastrointestinal tract, stomach ulcer;
  • Problems with hearing or vision, or having suffered visual impairments, visual ailments;
  • Anatomical pathologies of the penis.


Levitra is rapidly absorbed. The maximum concentration was noted in the blood 60 minutes after admission. The active substance has a 95% reversible binding to plasma proteins. The metabolism of the active substance of the drug occurs mainly with the participation of liver enzymes. It is excreted from the body through the gastrointestinal tract (up to 95%) and the kidneys.

The half-life of the active substance averages from 4 to 5 hours. In patients with mild and moderate renal failure, the distribution and excretion of the drug are at the same level as that of healthy patients. In patients aged over 65 years, the clearance of the active substance was considerably reduced.


The dosage of the drug is prescribed individually by the attending physician. It is necessary to strictly adhere to the instructions of the specialists and instructions for use. The dosage of the medication depends on the concentration of the active substance.

Adults: inside, regardless of food intake, the recommended single dose is 10 mg. Take the tablet 60 minutes before alleged sexual contact, no more than once a day.

Adults (over 65 years): inside, regardless of food intake, the recommended single dose is 5 mg (dosage can be changed based on consultation with a specialist). Take 60 minutes before alleged sexual contact, no more than once a day.

Children (under 16 years): use of Levitra is not recommended.

It is recommended to remove the tablet from the package immediately before use. Do not squeeze the tablet through the foil. Do not break, do not crumble, and do not chew. The use of grapefruit juice is not recommended during treatment. Substances contained in grapefruit and grapefruit juice can increase the chances of the side effects of this drug.


In case of an overdose, pain in the lower back, muscle pain and visual impairment may occur.

Interaction with other drugs

The use of Levitra with nitrate-containing drugs that are used for the treatment of heart diseases and are based on nitroglycerin, isosorbide dinitrate, isosorbide mononitrate is excluded. When used with Levitra, Nitrate-containing drugs with concomitant can cause a sudden and severe reduction in blood pressure.

Exclude the use of any other drugs for the therapy of erectile dysfunction based on alprostadil, yohimbine, sildenafil, tadalafil. Before using Levitra, it is necessary to inform the treating doctor regarding the personal status of the taking of any of the drugs listed above.

Pregnancy and lactation

The drug is not intended for the treatment of diseases in women. Data on the dangers of using the drug during pregnancy and lactation are not available.

Side effects

In the absence of contraindications, the drug is well tolerated. Possible side effects are:

  • Redness of the face, neck or chest;
  • A runny nose, nasal congestion;
  • Headache, dizziness;
  • Pain, tingling, feeling of heaviness or a lack of sensitivity in the chest, arms, neck or chin;
  • Back pains;
  • Sweating, upset stomach, nausea, general weakness;
  • Arrhythmia;
  • Swelling of the hands and feet;
  • Changes in visual perception, unexpected loss of vision;
  • Convulsions;
  • Painful erection, prolonged erection of over four hours (priapism);
  • Ringing in the ears;
  • Allergic reactions;
  • Quincke’s edema.

To avoid the occurrence of these side effects, avoid drinking alcohol.

If any side effects occur, seek medical attention immediately.